diff --git a/proxy/tun/handler.go b/proxy/tun/handler.go
index 1e8e030e6..a177ba40a 100644
--- a/proxy/tun/handler.go
+++ b/proxy/tun/handler.go
@@ -80,6 +80,12 @@ func (t *Handler) Init(ctx context.Context, pm policy.Manager, dispatcher routin
 				return nil
 			}
 			return c.Control(func(fd uintptr) {
+				_, ipStr, _ := net.SplitHostPort(address)
+				ip := net.ParseIP(ipStr)
+				// skip loopback
+				if ip != nil && ip.IsLoopback() {
+					return
+				}
 				err := setinterface(network, address, fd, iface)
 				if err != nil {
 					errors.LogInfoInner(context.Background(), err, "[tun] falied to set interface")